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Genicular Artery Embolization

Introduction

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Genicular Artery Embolization (GAE) is an innovative, minimally invasive, image-guided procedure designed to treat chronic knee pain caused by osteoarthritis.

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GAE is particularly suitable for patients who are not yet ready for knee replacement surgery but continue to experience significant pain, stiffness, and reduced mobility despite conservative treatments.

What is GAE?

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GAE targets the small blood vessels (genicular arteries) that supply the knee joint. In osteoarthritis, these vessels contribute to inflammation and pain within the joint lining.

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By selectively reducing blood flow to the inflamed areas, GAE helps decrease inflammation and pain, leading to improved knee function.

The procedure is performed under local anaesthesia with light sedation, and most patients go home the same day.

How does GAE work?

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  1. Small puncture – A tiny puncture is made in the groin (or wrist) artery.

  2. Catheter insertion – A thin catheter is carefully guided to the arteries supplying the knee using X-ray guidance.

  3. Embolization – Tiny particles are injected to selectively block blood flow to inflamed tissue within the knee joint.

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This targeted treatment reduces inflammation and relieves pain while preserving normal knee structures.

Who is a good candidate for GAE?

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GAE may be suitable for people who:

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  • Are 40 years or older

  • Have moderate to severe knee pain due to osteoarthritis

  • Experience knee stiffness, tenderness, or swelling

  • Have not found adequate relief from medications, physiotherapy, or injections

  • Are not ready for knee replacement surgery or wish to delay it

  • A detailed clinical assessment and imaging review are performed before recommending treatment.

Benefits of Genicular Artery Embolization

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  • Minimally invasive – no major surgery

  • No joint replacement or implants

  • Effective pain relief in most patients

  • Daycase procedure – no overnight hospital stay

  • Faster recovery compared to surgical options

Success rates and outcomes

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  1. Over 90% of patients report significant reduction in pain and improvement in daily function

  2. Benefits typically last 1–3 years, with some patients experiencing longer-lasting relief

  3. The procedure can be repeated safely if symptoms recur

What to expect during and after the procedure

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Before the procedure:

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  1. Performed under local anaesthesia with light sedation

  2. Procedure duration is approximately 1–2 hours

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After the procedure:

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  1. Discharge on the same day

  2. Light activities may be resumed within 1 week

  3. Avoid high-impact activities (such as running or jumping) for 2 weeks

  4. Gradual improvement in pain and mobility over weeks to months

Success rates and outcomes

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  1. Over 90% of patients report significant reduction in pain and improvement in daily function

  2. Benefits typically last 1–3 years, with some patients experiencing longer-lasting relief

  3. The procedure can be repeated safely if symptoms recur

Is GAE safe?

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GAE has a lower risk profile compared to knee replacement surgery.

Possible minor side effects include:

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  1. Bruising at the puncture site

  2. Temporary knee discomfort

  3. Localised swelling

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Serious complications are uncommon, and most side effects are temporary.

Why choose GAE at Nairobi Interventional Radiology Services?

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  1. Expertise in advanced, image-guided minimally invasive treatments

  2. Modern angiography facilities

  3. Patient-focused care with emphasis on safety and comfort

  4. Collaboration with orthopaedic specialists when required

Ready for pain relief?

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If knee pain from osteoarthritis is affecting your quality of life and you wish to avoid or delay surgery, Genicular Artery Embolization may offer effective, long-lasting relief.

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Frequently Asked Questions

What is Genicular Artery Embolization (GAE)?
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Genicular artery embolization (GAE) is a minimally invasive procedure used to treat chronic knee pain caused by osteoarthritis. Osteoarthritis is a degenerative joint disease that leads to the breakdown of cartilage in the knee, causing inflammation, pain, stiffness, and swelling.
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Who is suitable for Genicular Artery Embolization?
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GAE is most suitable for individuals:
Over the age of 40.
Suffering from moderate to severe knee pain due to osteoarthritis.
Experiencing knee tenderness, stiffness, and swelling.
Who have not found relief from conservative treatments like medications, physical therapy, or knee injections.

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How is Genicular Artery Embolization performed?
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The procedure is performed under local anesthesia. Here’s how it’s done:
A catheter is inserted into the femoral artery (located in the groin).
The catheter is carefully navigated toward the genicular arteries, which supply blood to the knee joint.
Embolic agents (tiny particles) are injected into the arteries to block blood flow, reducing inflammation and pain.

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What are the risks of Genicular Artery Embolization?
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Compared to traditional knee replacement surgery, GAE has:
Lower risk of bleeding, infections, and other complications.
Any complications that do occur are typically minor and may include bruising, discoloration, or localized discomfort at the treatment site.

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What is the recovery time for Genicular Artery Embolization?
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GAE is a short procedure that typically lasts 1-2 hours.
You can return home the same day.
Light activities can generally be resumed within one week.
We recommend avoiding high-impact activities (like running or jumping) for at least two weeks after the procedure.

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How long does the effect of Genicular Artery Embolization last?
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While GAE does not provide a permanent cure for knee osteoarthritis, it offers significant pain relief for 1-3 years on average. Some patients may experience longer-lasting benefits.
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What is the success rate for Genicular Artery Embolization?
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GAE has a success rate of over 90%. Most patients experience significant pain reduction and improved knee function following the procedure.

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